Flea Protection | Zoetis US

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Simparica works fast to provide rapid relief for pets with existing flea infestations. In studies, Simparica started killing fleas within 3 hours. By 8 hours, fleas were virtually eliminated with a reduction of live fleas of ≥96.2% through day 35.

Dogged flea protection

In 3 separate well-controlled laboratory studies, Simparica chewables demonstrated 99.8% to 100% effectiveness against weekly flea reinfestations for a full 5 weeks.¹

Percentage Reduction of C. felis Counts: Simparica vs Placebo¹

IMPORTANT SAFETY INFORMATION
Simparica is for use only in dogs, 6 months of age and older. Simparica may cause abnormal neurologic signs such as tremors, decreased conscious proprioception, ataxia, decreased or absent menace, and/or seizures. Simparica has not been evaluated in dogs that are pregnant, breeding or lactating. Simparica has been safely used in dogs treated with commonly prescribed vaccines, parasiticides and other medications. The most frequently reported adverse reactions were vomiting and diarrhea. See full Prescribing Information.

Reference:
^{1. Six RH, Geurden T, Packianathan R, et al. Evaluation of the effectiveness of a novel oral formulation of sarolaner (Simparica™) for the treatment and control of fleas on dogs. Vet Parasitol. 2016;222:18-22.}

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