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SIMBADOL buprenorphine injection
24-hour continuous surgical pain control for cats

UNDERSTANDING
ACUTE FELINE PAIN

Assessing pain in cats is challenging because they are known for hiding pain as a survival instinct. As a result, feline pain is often underdiagnosed.

Understanding Cat Pain Understanding Cat Pain

Subtle behavioral and physiological changes are often the only indicators of feline pain.

BEHAVIORAL

hunched posture

hiding

changes in facial expression

lowered ears

increased vocalization

PHYSIOLOGICAL

hypertension

tachycardia

tachypnea

How does SIMBADOL manage
feline pain?
LEARN HOW

Feline Acute Pain Scales

There are now two pain scales validated to assess surgical pain in the cat, the UNESP-Botucatu Multidimensional Composite Pain Scale and the Glasgow Composite Measure Pain Scale–Feline.4,5 The Colorado State University Feline Acute Pain Scale is also a useful tool to assess pain in cats, although it has not been validated.3 Regardless of how you are assessing feline postoperative pain, we can assume that cats will feel pain.

Pain processing is similar in all mammals.

It follows four distinct steps.

Feline Pain Processing  Feline Pain Processing
1
Transduction
Noxious pain stimulus (as from a surgical procedure) is converted into nerve impulses.
2
Transmission
These impulses are transmitted from where the pain originated to the spinal cord.
3
Modulation
The impulses are either inhibited or amplified within the dorsal horn of the spinal cord.
4
Perception
Pain is recognized by the brain.

Assessing and alleviating pain in cats is not only a core goal of veterinary medicine, but successfully controlling the pain of a surgical procedure can also strengthen the human-animal bond and even help reinforce the relationship between veterinarian, client and patient.

Veterinarians tend to agree that feline pain can last longer than 24 hours after common surgical procedures.3 SIMBADOL (buprenorphine injection) is the first and only FDA-approved opioidto provide once-daily 24-hour control of postoperative pain in cats. SIMBADOL works well with other induction and maintenance anesthesia drugs and can be incorporated into any feline surgical protocols.

SIMBADOL works along the pain pathway to safely and effectively control pain in your feline patients.
LEARN HOW
Try SIMBADOL Today

Try SIMBADOL Today

24-hour. The only FDA Approved buprenorphine for cats.
ONE INJECTION ADMINISTERED IN-CLINIC
24 HOURS OF CONTINUOUS PAIN CONTROL
UP TO 3 ONCE-DAILY SUBCUTANEOUS DOSES FOR A TOTAL OF 72 HOURS OF PAIN CONTROL1
DEMONSTRATED SAFETY AND EFFICACY IN MORE THAN 200 CATS TREATED WITH SIMBADOL1
COST COMPETITIVE
100% COMPLIANCE
ORDER SIMBADOL

Have Questions?

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INDICATION: SIMBADOL is indicated for the control of postoperative pain associated with surgical procedures in cats.

See References for detailed information about research studies referenced on this website.

IMPORTANT SAFETY INFORMATION: Due to serious human safety and abuse concerns, including physical or psychological dependence, life-threatening respiratory depression and additive CNS depressant effects, read the full prescribing information before using this drug, including the complete Boxed Warning. Not for use in humans. Hospital staff should be trained in the handling of potent opioids and should avoid accidental exposure. SIMBADOL has not been evaluated in breeding, pregnant, or lactating cats, in cats younger than 4 months of age or moribund cats. Do not use in cats with known hypersensitivity to buprenorphine hydrochloride or any of the components of SIMBADOL, or known intolerance to opioids. Use with caution in cats with impaired hepatic function. Adverse reactions may include hyperthermia, tachycardia, hypotension, hypertension, hypothermia, anorexia, and hyperactivity. For more safety information, refer to the full Prescribing Information.

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Zoetis Services LLC. All rights reserved. SIM-00052